Platelet antigens in varicella associated thrombocytopenia.
نویسنده
چکیده
Serum IgG or, predominantly, IgM antibody binding to electrophoretically separated normal platelet membrane protein antigens were detected by immunoblotting in five children with thrombocytopenia associated with varicella. Glycoproteins GPIb, GPIIb, GPIIIa, and other 25-260 kilodalton (kDa) proteins were identified as target antigens, suggesting a transient autoimmune mechanism causing the thrombocytopenia.
منابع مشابه
Platelet antigens in varicella associated thrombocytopenia
1 Feusner JH, Slichter SJ, Harker LA. Mechanisms of thrombocytopenia in varicella. Am J Hematol 1979;7: 255-64. 2 Espinoza G, Kuhn C, Viral infection of megakaryocytes in varicella with purpura. Am J Clin Pathol 1974;61:203-8. 3 Winiarski J. IgG and IgM antibodies to platelet membrane glycoprotein antigens in acute childhood idiopathic thrombocytopenic purpura. BrJ Haematol 1989;73:88-92. 4 Win...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 65 1 شماره
صفحات -
تاریخ انتشار 1990